It is with profound sadness that we announce the passing of Dr. Carlo Ballatore, Ph.D., a cherished professor at the University of California, San Diego’s Skaggs School of Pharmacy and Pharmaceutical Sciences. Dr. Ballatore tragically lost his life in an accident on April 2, 2025, while hiking in Big Sur, California, accompanied by his son, Paolo
A Life Dedicated to Science and Education
Dr. Ballatore’s academic journey began in Rome, Italy, where he earned his “Laurea” in Chemistry and Pharmaceutical Technologies from the University of Rome “La Sapienza” between 1990 and 1995. He furthered his education with a Ph.D. in Medicinal Chemistry from Cardiff University in the United Kingdom, under the mentorship of Professor C. McGuigan. His postdoctoral training took place at the University of Texas MD Anderson Cancer Center in Houston, where he worked in the laboratory of Professor D. Farquhar.
Before joining UC San Diego, Dr. Ballatore served as the head of medicinal chemistry at the Center for Neurodegenerative Disease Research at the University of Pennsylvania from 2005 to 2016. His tenure at UC San Diego was marked by significant contributions to the field of medicinal chemistry, particularly in the design and synthesis of small molecules aimed at treating neurodegenerative diseases such as Alzheimer’s. His research also extended to combating parasitic diseases like African Sleeping Sickness.
Dr. Ballatore’s work was characterized by a collaborative, multidisciplinary approach, focusing on the development of small molecules as research tools or potential therapeutics. His efforts in structure-activity and structure-property relationship studies were instrumental in advancing drug discovery programs.
A Legacy of Mentorship and Compassion
Beyond his scientific achievements, Dr. Ballatore was revered for his mentorship and dedication to his students and colleagues. He co-led graduate courses in drug discovery and development, shaping the minds of future pharmaceutical scientists. His commitment to education and research left an indelible mark on the UC San Diego community. (
Remembering a Beloved Family Man
Dr. Ballatore is survived by his wife, Juliana Guerra, and their children, Isabella and Paolo. In the wake of his untimely passing, the family has faced significant challenges, including financial hardships that led Isabella to withdraw from university to support the family. A GoFundMe campaign has been established to assist with the children’s education expenses, honoring Dr. Ballatore’s wish for his children to pursue higher education. (
Dr. Carlo Ballatore’s legacy is one of scientific excellence, unwavering mentorship, and deep familial love. His contributions to medicinal chemistry and the lives he touched will continue to inspire and guide future generations.